MYC2 Transcription Factors TwMYC2a and TwMYC2b Negatively Regulate Triptolide Biosynthesis in Tripterygium wilfordii Hairy Roots
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منابع مشابه
Determination of Triptonide and Triptolide in Multi-glycosides Tripterygium Wilfordii Tablets by Capillary Electrophoresis
A capillary electrophoresis method has been established for the determination of triptonide and triptolide in Multi-glycosides Tripterygium wilfordii tablets. Capillary separation was carried out by using 0.01mol L borax + 0.02 mol L boric acid + 0.02 mol L SDS (pH = 8.0) as the buffer, a fused – silica capillary tube column (60.2 cm × 75μm id. 52.6 cm of effective length) as the separation cha...
متن کاملIsolation and Purification of Triptolide from the Leaves of Tripterygium wilfordii Hook F
Triptolide is an important active component of Tripterygium wilfordii Hook F (TWHF) and possesses anti-inflammatory, immunosuppressive, male anti-fertility, and anticancer properties. A new method combining different techniques, including solid-liquid extraction, liquid-liquid partition, column chromatography and high-speed counter-current chromatography (HSCCC) but avoiding the use of chlorofo...
متن کاملA Mechanistic Overview of Triptolide and Celastrol, Natural Products from Tripterygium wilfordii Hook F
Triptolide and celastrol are predominantly active natural products isolated from the medicinal plant Tripterygium wilfordii Hook F. These compounds exhibit similar pharmacological activities, including anti-cancer, anti-inflammation, anti-obesity, and anti-diabetic activities. Triptolide and celastrol also provide neuroprotection and prevent cardiovascular and metabolic diseases. However, toxic...
متن کاملTerpene alkaloids from Tripterygium wilfordii.
Two new sesquiterpene alkaloids, 1beta-hydroxy-2beta,5alpha,11-triacetoxy-7beta-nicotinoyl-8beta-benzoyl-dihydroagarofuran, and 1beta,5alpha,11-triacetoxy-7beta-nicotinoyl-8beta-benzoyl-dihydroagarofuran were isolated from the xylem of Tripterygium wilfordii, together with six known compounds. Their structures were elucidated on the basis of spectroscopic studies.
متن کاملArabidopsis basic helix-loop-helix transcription factors MYC2, MYC3, and MYC4 regulate glucosinolate biosynthesis, insect performance, and feeding behavior.
Arabidopsis thaliana plants fend off insect attack by constitutive and inducible production of toxic metabolites, such as glucosinolates (GSs). A triple mutant lacking MYC2, MYC3, and MYC4, three basic helix-loop-helix transcription factors that are known to additively control jasmonate-related defense responses, was shown to have a highly reduced expression of GS biosynthesis genes. The myc2 m...
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ژورنال
عنوان ژورنال: Plants
سال: 2021
ISSN: 2223-7747
DOI: 10.3390/plants10040679